Dr. HingHau Tsang's Crusade on Nutrition
Newsletter #49
--- Advance in Anti-aging - Homeopathic Human Growth Hormone
Human Growth Hormone
(hGH) or somatotropin, is the most abundant hormone secreted by the pituitary gland in the brain and is important in stimulating and regulating growth. hGH is the hormone of youth praised by the American Academy of Anti-Aging Medicine as the most effective way of slowing and reversing the aging process. Growth hormone stimulates the body's regenerative building of muscle and bone tissue. Increased lean muscle mass, higher energy levels, and a greater sense of well being are associated with optimal levels of growth hormone. hGH stays in the bloodstream for only a few minutes, however, this is long enough to stimulate its uptake by the liver, where it stimulates production of insulin-like growth factor-1 (IGF-1) or somatomedin C. IGF-1, a small protein peptides, is responsible for most of the actions of human growth hormone, such as stimulating muscle development, strengthening cartilage, increasing bone density, boosts the immune system, strengthens the skin and increasing mental clarity. IGF-1 has been shown in experimental studies to repair and reconnect severed nerve endings at a distance of up to 6 mm-a feat previously unheard of! IGF-1 has increased motor neuron activity in spinal cord cells grown in the laboratory. IGF-1 appears to stimulate growth in nerve cells, increasing the nervous system's speed in conducting signals-an important goal for keeping the brain young. These factors are essential for repair and regeneration of the body's cells and tissues and maintaining normal growth. Growth factors are produced by the liver in large numbers in youth. After all, our bodies are constantly in a state of breakdown, repair and rebuilding. In youth these processes are at a peak. As we age, the production of growth hormone and growth factors drops by up to 10% per decade, so that by the time we are 65 we have less than 1/2 the ability to repair and regenerate our body's tissues. This greatly contributes to the acceleration of the aging process. The decline of growth hormone with age is directly associated with many of the symptoms of aging. These include wrinkling, gray hair, decreased energy, and diminished sexual function. Lack of growth hormone contributes to increasing body fat, cardiovascular disease, osteoporosis, and an inclination toward other aging-related diseases such as cancer and organ failure.In July 1990, a landmark study was published in The New England Journal of Medicine. Daniel Rudman, M.D., injected 21 men between the ages of 60 and 80 with supplemental HGH, three times a week for six months, and compared the results with nine men in a control group. The men receiving HGH showed a strong correlation between the degree of IGF-1 rise and perceived benefits by the patients who all showed a marked improvement in health and appearance. They gained an average of 8.8% in muscle mass, lost an average of 14% body fat and increased their skin thickness -- without changing their diets. Dr. Rudman commented that the changes in body composition reversed approximately 10 to 30 years of aging
Problems Associated with Too Much hGH
Gigantism and acromegaly are excellent human models for understanding the dangers of excessive GH. Gigantism is caused by the presence of excess hGH before puberty, with consequences that can include extreme height, abnormal proportions of the body to the arms and legs, and early death. Acromegaly is caused by the presence of excess hGH after full skeletal growth has occurred. Both are accompanied by a host of abnormal metabolic changes, such as impaired glucose intolerance, diabetes mellitus, osteoporosis, respiratory problems, decreased bone mineral density, cardiac arrythmias, and hypertension. Growth hormone can also stimulate overgrowth of connective tissue, leading to joint pain, arthritis and carpal tunnel syndrome. It can also cause edema (fluid retention) and hypertension. Patients with pituitary tumors that secrete excessive amounts of growth hormone have an increased incidence of tumors of the stomach and colon. Scientists are divided on whether HGH might increase cancer risk by promoting growth of tumor cells. Some endocrinologists believe that all of the adverse side effects could be avoided by using much smaller amounts of growth hormone.
Problems Associated with administrating hGH
hGH was hard to obtain and very expensive -- it could only be obtained from human and animal cadavers' pituitary glands. hGH itself was reserved for the treatment of children who failed to grow to normal height. In the mid-1980s, two drug companies were able to produce hGH through recombinant DNA technology, making it widely available for research and treatment. Recombinant DNA technology means that special DNA is inserted into the DNA of yeast and bacteria, which causes the organisms to reproduce a large supply of growth hormone identical in structure to the body's own growth hormone.
The FDA now allows American doctors to use hGH for anti-aging treatment. Still, few people could afford access to this hormone, which costs up to $1000 per month. The hormone must be injected once or twice daily and be closely supervised by a medical doctor.
Many products were introduced to the market and made affordable for consumers to take orally. These are so called hGH releasers - compound that is taken orally (or as a spray form) to stimulate the release of the body's own growth hormone. These products usually contain 15-20 amino acids (Glutamine, Arginine, Pyroglutamate, Glycine, Lysine, Tyrosine, GABA etc) which are supposed to induce growth hormone secretion. Many of these products have added pituitary, hypothalamus and liver extract from animal source (Bovine). They are potentially dangerous. One is the well documented dangers of human-brain wasting ailments (leading to long suffering prior to early death) from human consumption of these high risk animal parts. Other being the concerns of introducing Bovine Spongiform Encephalopathy (BSE or Mad Cow Disease). There has been report of more people getting an acquired form of human BSE or Creutzfeldt-Jakob disease (CJD) from taking human growth hormone that was extracted from bovine pituitary glands. None of these products have been tested in US for its long term safety and effectiveness. There are no known double blind, placebo controlled study in US on any of these products.
Now, a high-tech version of homeopathy promises the same anti-aging effects. This unusual marriage of technology and homeopathy is making the benefits of this hormone available to everyone. This is the only OTC hGH product on the market today backed by double blind, placebo controlled clinical studies performed in the US, peer reviewed and published in December 1999 "Alternative and Complementary Therapies".
Introducing ---
Homeopathic Human Growth Hormone (HhGH)
Homeopathic Cell Signal Enhancer Human Growth Hormone (CSE) were developed, clinically tested and patented by former NIH (National Institute of Health) scientist, Dr. Barbara Brewitt. CSE-hGH contains USP standardized recombinant human growth hormone in homeopathic formulations. It contains actual human growth hormone with an oral formulation that was at least 4000 times lower in concentration than an injectable hGH. It is not obtained from human cadavers or animal parts. Homeopathy is a form of medicine that uses infinitesimal doses of natural substances to stimulate the body's own immune system. The advantage to this new breakthrough is that you don't have to go to a doctor to receive injections of growth hormone. This represents a major breakthrough in reduction of health-care costs for both healthy and chronically ill individuals.
Dr. Barbara Brewitt has completed Double-Blind Studies to evaluate the efficacy of homeopathic human growth hormone as an oral, chewable tablet. Some of the benefits seen after a six week program of oral homeopathic hGH therapy are:
People who took one tablet, three times daily for two to four weeks, showed an 8 to 23% increase in IGF levels in the blood. This indicates a physiological activity by growth hormone. Similar to injectable hGH, chewable tablets of HhGH had positive effects on lean body mass, produced weight and fat loss, relieved fatigue, produced body shape changes, and improved psychologic well-being. Homeopathic hGH also improved self-perceived measures related to quality of life significantly, such as energy increase, weight loss, improved vision, increased libido, improved sleep quality, improved breathing, elimination of joint pains and improved skin softness. Thus, an oral formulation provided some of the same benefits of the injectable hGH without its side effects. Their clinical results suggest that homeopathic hGH provides a safe, effective, pure and affordable method to optimize physical and mental functioning.
Homeopathic hGH could play useful roles in the management of menopause and chronic illness such as depression or AIDS. (Dr. Brewitt conducted in 1995, a four-month, double-blind, placebo-controlled study of thirty HIV-positive patients. The result was positive) Result in one double-blind, placebo-controlled trial showed applications for PMS/menopause, as it eliminated uterine cramping, breast tenderness, headaches, general irritability and hot flashes. Homeopathic growth factors offer an intriguing, new and safe option to both healthy and chronically ill people and may also offer inexpensive and revolutionary access to the fountain of youth. No long-term side effects have been noted in 2+ years of research.
Note
Homeopathic Human Growth Hormone acts to signal the liver to synthesize more IGF-1 (Insulin-like growth factor-1). However, cells become resistant to taking up IGF-1 as we become older or stressed or exposed to toxins etc. IGF-1 receptor sites are not working properly. IGF-1 will help to sensitize the cell receptor site to uptake the IGF1 that is produced from the liver. Homeopathic Human Growth Hormone alone will not work well in some people (Men and women) with hormone imbalances. These people are those with significant environmental sensitivities and women with significant symptoms of PMS or menopause. Be sure to use IGF-1.
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