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Home of Natural Remedies & Nutritional Information
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Cogni-flex Nutritional support for healthy mental
function Dosage 100
mcg Size 60 capsules Direction Ingredient Each Capsule Contains: |
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About Cogni-flex The four nutrients in Cogni-flex support the
structure and function of cognitive processes in several ways. They support
neurotransmitter metabolism, enhance vascular circulation to the brain, and
help maintain structure and function of nerve cell membranes. Huperzine A is a 100% natural - from an extract of Chinese club
moss (Huperzia serrata), and is one of the most exciting new products for
memory and cognition, particularly for older men and women. Huperzine A supports memory and concentration
and healthy brain functioning by preserving levels of the important
neurotransmitter, acetylcholine. With BioPerine, a natural, standard extract
of black pepper, to help the body absorb the active nutrient more
efficiently. Huperzine A may significantly improve memory
and mental function -- with none of the negative side effects of commonly
prescribed prescription drugs. HupA has been used in Chinese medicine for
centuries to treat inflammation and fever. HupA works in a similar fashion to
the two most commonly prescribed drugs for Alzheimer's disease, tacrine
(Cognex) and donepezil (Aricept). All three inhibit the breakdown of
acetylcholine. While all three have been shown to enhance memory, boost
acetylcholine and protect brain cells from toxins, HupA has none of the
significant side effects of the prescription drugs, which can cause nausea,
vomiting, excess sweating and salivation, and liver damage. HupA also has a
longer duration than both of these drugs. Several studies have shown that
HupA improves brain function in patients with dementia. HupA seems to have
additional properties that may help it to slow the progression of
Alzheimer's. One study showed that it can slow the formation of a harmful
kind of plaque, a buildup of protein deposits in the brain. Other studies
indicate that it can protect brain cells from glutamate, a neurotransmitter
that becomes toxic when it is secreted in large amounts. Some research also
indicates that Huperzine A helps to block the process of inflammation that
occurs as Alzheimer's disease progresses. The recommended dose of Huperzine A
is 100-200 mcg per day in divided doses. Ginkgo Biloba extract is also reported to inhibit the tendency of red blood
cells to stick together (clumping), thereby enhancing the functional fluidity
of the blood. Improving the functional circulation to the brain and other
parts of the body allows for better oxygen and glucose uptake, with
subsequent enhancement of memory and mental functions. Phosphatidylserine: This phospholipid, found in high concentrations in the
nervous system, helps maintain functional fluidity of nerve cell membranes,
thus providing for optimal transport of nutrients and other compounds across
the cell membrane. It is also used in the repair and regeneration of nerve
cells. Phosphatidylserine also appears to help the body counterbalance
excessive release of adrenocorticotropic hormone (ACTH), adrenaline, and
cortisol which are released in response to stress. Acetyl-L-carnitine: This acetylated high energy ester of the amino acid L-carnitine contributes its acetyl group to the production of acetylcholine, the primary neurotransmitter for memory and thought. The enzyme that makes acetylcholine from acetyt groups and choline is choline acetyl transferase. The activity of this important enzyme has a tendency to decline with age, causing low acetylcholine levels which in turn are thought to contribute to the impairment of brain function that is associated with aging. Research has also found that acetyl-L-carnitine is active in optimizing the functioning of cerebral blood flow, as well as of nerve cell membranes. |
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Warning: Internal use not advised during pregnancy or
nursing. Keep out of the reach of children. Cautions: Huperzine A is generally non-toxic. No
significant side effects reported. Mild, transient headaches may occur during
the first 2-3 days of taking Ginkgo Biloha in people with previously
insufficient cerebral blood tlow, indicating the activity of this herb. Ginkgo Biloba may potentiate the action of anticoagulants
and central nervous system drugs. Some cases of dizziness and the potential for nausea or
excessive salivation are possible. It is probably better to use
intermittently. Before stopping Huperzine A completely, it is safer to taper
dose gradually over a week. Scientific Evidence A double-blind placebo-controlled study
evaluated 103 people with Alzheimer's disease who received either huperzine A
or placebo twice daily for 8 weeks.18 About 60% of the treated participants showed
improvements in memory, thinking, and behavioral functions compared to 36% of
the placebo-treated group, and the difference was significant. Benefits were also seen in an earlier
double-blind trial using injected huperzine in 160 individuals with dementia
or other memory disorders.19 Huperzine is also reportedly helpful for
improving memory in healthy individuals. A double-blind trial of 34 matching
pairs of junior middle school students reported improvements in memory in the
treated group.20 References 1. Zhang RW, Tang XC, Han YY,
et al. Drug evaluation of huperzine A in the treatment of senile memory
disorders [in Chinese, English abstract]. Chung Kuo Yao Li Hsueh Pao.
1991;12:250-252. 2. Cheng DH, Tang XC.
Comparative studies of huperzine A, E2020, and tacrine on behavior and
cholinesterase activities. Pharmacol Biochem Behav. 1998;60:377-386. 3. Cheng DH, Ren H, Tang XC.
Huperzine A, a novel promising acetylcholinesterase inhibitor. Neuroreport.
1996;8:97-101. 4. Xiong ZQ, Tang XC. Effect of
huperzine A, a novel acetylcholinesterase inhibitor, on radial maze
performance in rats. Pharmacol Biochem Behav. 1995;51:415-419. 5. Zhi QX, 6. Zhu XD, Giacobini E. Second
generation cholinesterase inhibitors: effect of (L)-huperzine-A on cortical
biogenic amines. J Neurosci Res. 1995;41:828-835. 7. Zhang GB, Wang MY, Zheng JQ,
et al. Facilitation of cholinergic transmission by huperzine A in toad
paravertebral ganglia in vitro [in Chinese, English abstract]. Chung Kuo Yao
Li Hsueh Pao. 1994;15:158-161. 8. Laganiere S, Corey J, Tang
XC, et al. Acute and chronic studies with the anticholinesterase Huperzine A:
effect on central nervous system cholinergic parameters. Neuropharmacology.
1991;30:763-768. 9. Tang XC, De Sarno P, Sugaya
K, et al. Effect of huperzine A, a new cholinesterase inhibitor, on the
central cholinergic system of the rat. J Neurosci Res. 1989;24:276-285. 10. Tang XC, Han YF, Chen XP,
et al. Effects of huperzine A on learning and the retrieval process of
discrimination performance in rats [in Chinese]. Chung Kuo Yao Li Hsueh Pao. 1986;7:507-511. 11. Guan LC, Chen SS, Lu WH, et
al. Effects of huperzine A on electroencephalography power spectrum in
rabbits [in Chinese, English abstract]. Chung Kuo Yao Li Hsueh Pao.
1989;10:496-500. 12. Lu WH, Shou J, Tang XC.
Improving effect of huperzine A on discrimination performance in aged rats
and adult rats with experimental cognitive impairment [in Chinese]. Chung Kuo
Yao Li Hsueh Pao. 1988;9: 11-15. 13. Wang YE, Feng J, Lu WH.
Pharmacokinetics of huperzine A in rats and mice [in Chinese]. Chung Kuo Yao
Li Hsueh Pao. 1988;9:193-196. 14. Wang YE, Yue DX, Tang XC.
Anti-cholinesterase activity of huperzine A [in Chinese]. Chung Kuo Yao Li
Hsueh Pao. 1986;7:110-113. 15. Zhu XD, Tang XC.
Improvement of impaired memory in mice by huperzine A and huperzine B [in
Chinese]. Chung Kuo Yao Li Hsueh Pao. 1988;9:492-497. 16. Zhu XD, Tang XC.
Facilitatory effects of huperzine A and B on learning and memory of spatial
discrimination in mice [in Chinese]. 17. Yan XF, Lu WH, Lou WJ, et
al. Effects of huperzine A and B on skeletal muscle and the
electroencephalogram [in Chinese]. Chung Kuo Yao Li Hsueh Pao.
1987;8:117-123. 18. Xu SS, Goa ZX, Weng Z, et
al. Efficacy of tablet huperzine-A on memory, cognition, and behavior in Alzheimer's
disease. Chung Kuo Yao Li Hsueh Pao. 1995;16:391-395. 19. Zhang RW, Tang XC, Han YY,
et al. Drug evaluation of huperzine A in the treatment of senile memory
disorders [in Chinese; English abstract]. Chung Kuo Yao Li Hsueh Pao.
1991;12:250-252. 20. Sun QQ, Xu SS, Pan JL, et al. Huperzine-A capsules enhance memory and learning performance in 34 pairs of matched adolescent students [abstract]. Chung Kuo Yao Li Hsueh Pao. 1999;20:601-603. |
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Place
your order Cogni-Flex 100mcg 60 cap $46 Add To Cart Repeat Customer ! Log-in to order Or Mail In Your Order Form Here International Customer: We do not ship internationally |
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Disclaimer This is a statement of nutritional support.
This statement has not been evaluated by the FDA. This product is not
intended to medically diagnose, treat, cure, or prevent any disease. Always
consult your health care provider before using any supplement. |
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