Adults take 1-2 capsules daily between meals or as directed by physician.

For motion sickness take two capsules 20 minutes before travel

Each Capsule Contains:
Ginger (Zingiber officinale) 250 mg.
Standardized 5% of total pungent compounds including the phenylalkylketones (particularly the two main, 3-methoxy-4 hydroxy aromatic compounds 6-gingerol and 6-shogaol) or 4% volatile oils. In a 100mg base of non-standardized Ginger.

If you are pregnant or nursing, seek the advice of your physician before using this product.

Ginger is thought to aid digestion and absorption of important food constituents and to protect and soothe the digestive system as a whole. In addition, ginger has notable antioxidant and enzyme activity. Ginger's effect on inflammation is documented in several studies. A possible mechanism of action involves a change in the synthesis of prostaglandins and leukotrines - hormonelike substances that mediate inflammation - therefore it can alleviate headache, pain and inflammation in osteoarthritis and fibromyalgia.

Besides its anti-inflammatory properties, it works well as a treatment for nausea and motion sickness. This is probably the use for which it is most valued, and is believed to be due to the volatile oil that gives ginger its characteristic pungency. Ginger is more effective than Dramamine for motion sickness and doesn't cause drowsiness as a side effect.

Effects of a Ginger Extract on Knee Pain in Patients With Osteoarthritis - Altman RD, Marcussen KC. Source: Arthritis Rheum. 2001;44(11):2531-2538

Objective: To evaluate the efficacy and safety of a standardized and highly concentrated extract of 2 ginger species, Zingiber officinale and Alpinia galanga, in patients with osteoarthritis (OA) of the knee.

Method: Two hundred sixty-one patients with OA of the knee and moderate-to-severe pain were enrolled in a randomized, double-blind, placebo-controlled, multicenter, parallel-group, 6-week study. After washout, patients received ginger extract or placebo twice daily, with acetaminophen allowed as rescue medication. The primary efficacy variable was the proportion of responders experiencing a reduction in "knee pain on standing," using an intent-to-treat analysis. A responder was defined by a reduction in pain of > or = 15 mm on a visual analog scale.

Result: In the 247 evaluable patients, the percentage of responders experiencing a reduction in knee pain on standing was superior in the ginger extract group compared with the control group (63% versus 50%; P = 0.048). Analysis of the secondary efficacy variables revealed a consistently greater response in the ginger extract group compared with the control group, when analyzing mean values: reduction in knee pain on standing (24.5 mm versus 16.4 mm; P = 0.005), reduction in knee pain after walking 50 feet (15.1 mm versus 8.7 mm; P = 0.016), and reduction in the Western Ontario and McMaster Universities osteoarthritis composite index (12.9 mm versus 9.0 mm; P = 0.087). Change in global status and reduction in intake of rescue medication were numerically greater in the ginger extract group. Change in quality of life was equal in the 2 groups. Patients receiving ginger extract experienced more gastrointestinal (GI) adverse events than did the placebo group (59 patients versus 21 patients). GI adverse events were mostly mild.

A double-blind comparative study that followed 1,489 individuals aboard a ship found ginger to be equally effective as various medications (Dimehydrinate with caffeine, meclozine with caffeine, and scopolamine).² Another double-blind study found equivalent benefit of ginger at a dose of 500 mg every 4 hours and dimenhydrinate 100 mg every 4 hours in a group of 60 passengers aboard a ship.³

1. Bliddal H, Rosetzsky A, Schlichting P, et al. A randomized, placebo-controlled, cross-over study of ginger extracts and ibuprofen in osteoarthritis. Osteoarthritis Cartilage. 2000;8:9-12.

2. Schmid R, Schick T, Steffen R, et al. Comparison of seven commonly used agents for prophylaxis of seasickness. J Travel Med.1994;1:203-206.

This is a statement of nutritional support. This statement has not been evaluated by the FDA. This product is not intended to medically diagnose, treat, cure, or prevent any disease. Always consult your health care provider before using any supplement.